• Home
• News
• List of Partners
• • Map of Partners
• List of Projects
• Research Activities
• Jobs
• Management

Initial Training Network - Chemical Bioanalysis

Roche Diagnostics GmbH

[ Back to list of partners ]

Projects

• Development of a new colorimetric RedOxindicator
• Influence of test strip architecture on diffusion processes important for chemistry performance
• Usage of upconverting phosphors in chemistry layers for the detection of analytes

Positions

Development of a new colorimetric RedOxindicator
Description:	In the function as a Post-graduate (m/w) in the field of developing of a new colorimetric RedOxindicator is the following assignment: • Design, synthesis and testing of new indicator types • Measurement in blood glucose test strips by photometric methods • Establishing a new indicator which works better then the current one • Using and synthesize of new dyes in g-scale for the detection of the analyte glucose • Improving of the current test strips
Requirements:	In the function as a Post-graduate (m/w) in the field of developing of an new colorimetric RedOxindicator you should bring up these requirements: • Master of Science in chemistry, especially organic synthesis chemistry with very good grades • Ability to synthesize new dyes in g-scale in the Organic Synthesis Group in Penzberg and Mannheim • Willing to learn layer coating techniques and measurement techniques for blood glucose measurements • Good communication skills in English; German are very helpful • Ability to work in a team and self-dependent as well Training opportunities (trainings for soft skills etc.) will be provided.
Position filled.

Influence of test strip architecture on diffusion processes
Description:	In the function as a Post Doc (m/w) in the field of Influence of test strip architecture on diffusion processes is the following assignment: • Production of specific glucose binders (e.g. proteins or other substances) in Penzberg and then investigation under specific questions of dry layer test strip architectures in Mannheim • Handling with specific binders like GBP (glucose-binding-protein), Apo-GOx and boronic acids • Working with several types of dispo architectures • Usage of binding events for the detection of blood glucose with a specific binder • Evaluation of binders in dry layers for blood glucose testing and the advantages • Analysis of glucose
Requirements:	In the function as a Post Doc (m/w) in the field of Influence of test strip architecture on diffusion processes you should bring up these requirements: • Ph.D of Science biochemistry with a very good background in protein chemistry • Ability to produce proteins in gram-scale by common methods (e.g. fermentation, precipitation, chromatography, protein conjugation) • Characterize proteins with physicochemical techniques in the Biotechnology Development group in Penzberg • Willing to learn layer coating techniques and investigation methods for dry layer analysis in Mannheim • Good communication skills in English; German are very helpful • Ability to work in a team and self-dependent as well Training opportunities (trainings for soft skills etc.) will be provided.
Position filled.

Upconverting phosphors in chemistry layers for detection of an analyte
Description:	In the function as a Post-graduate (m/w) in the field of up-converting phosphors in chemistry layers for detection of an analyte is the following assignment: • Design of the measuring optics in photometric measurements by sophisticated optical designs • Realization of methods like fluorescence detection • Implementation and appropriation measurement technique for up-converting phosphors • Evaluation of the dependencies of the energy transfer on concentrations, type of up-converting phosphors, dye and dye structure, distribution and the availability in layer • Applying of optical setups on the detector • Solving of problems in measure errors between illumination and detection
Requirements:	In the function as a Post-graduate (m/w) in the field of up-converting phosphor in chemistry layers for the detection of an analyte you should bring up these requirements: • Master of Science in physics or physical chemistry with very good grades • Well-founded knowledge especially in optical physics, optical microscopy and UV/Vis spectroscopy • Knowledge (chemistry / physics) on fluorescence and dyes • Experience in optical setups using LED’s, photodiodes, optical fibers, opto-mechanics and –electronics • Willing to build up an laboratory measurement setup in Mannheim for the evaluation of up-converting phosphors for the analyte detection in dry layers • Experience in data evaluation using Matlab is of advantage • Good communication skills in English; German is very helpful • Ability to work in a team and self-dependent as well Training opportunities (trainings for soft skills etc.) will be provided.
Position filled.